If the cricopharyngeal muscle (CPM) in your throat malfunctions or is impaired, this can cause you to have difficulty swallowing. The top valve of your esophagus (food pipe) is called the upper esophageal sphincter (UES), or pharyngoesophageal segment (PES). The Cricopharyngeal Muscle separates the esophagus and throat. Unlike most muscles, the Cricopharyngeal Muscle remains flexed and tightly closed unless nerves signal it to relax. This protects the throat and windpipe from food or liquid coming back up and inadvertently entering the lungs. For food, liquid, and saliva to enter the esophagus, the Cricopharyngeal Muscle needs to relax while these contents pass through into the esophagus.
If you have Cricopharyngeal Muscle dysfunction, you may experience:
CPM and UES dysfunction occur for varying reasons. It may result as a side effect of the normal aging process or due to changes in the Cricopharyngeal Muscle or nerve signaling pathways. Specifically, muscle enlargement (called hypertrophy), scarring of the muscle (called fibrosis) from radiation therapy or trauma, stroke, and reflux (heartburn) can all damage the swallowing mechanism at the UES.
To test for Cricopharyngeal Muscle and/or UES dysfunction, your ENT (ear, nose, and throat) specialist, or otolaryngologist, may examine your throat and larynx (voice box) by passing a small flexible camera through your nose. In addition, your ENT specialist may order an X-ray swallowing test called a modified barium swallow, esophagram, and/or manometry (pressure testing) of the valve area.
During the modified barium swallow, also known as a Videofluoroscopic Swallow Study (VFSS), you swallow various barium-coated food, liquid, and pills while a speech language pathologist takes X-ray video. For an esophagram, a radiologist looks at the esophagus with X-rays as barium is swallowed in order to evaluate esophageal function.
In Cricopharyngeal Muscle dysfunction, a narrowing of the valve may be seen, although narrowing of the PES may not be abnormal or require intervention. Manometry is a test that measures throat and esophageal pressures during swallowing by placing a thin tube through the nose into the esophagus and having patients swallow water. In Cricopharyngeal Muscle dysfunction, the valve may have high pressures at rest and/or during swallows.
There are numerous cricopharyngeal muscle dysfunction treatment options that can substantially improve your condition, including dilatation (stretching), oral medications, BOTOX® injection, and myotomy (cutting). Dilatation procedures are generally not permanent and allow for a trial period to see whether a treatment will be helpful. These can be done either with mild or no sedation, or under general anesthesia.
As with stretching, BOTOX injections into the Cricopharyngeal Muscle provide temporary results, generally for three to six months, by causing partial paralysis or weakening of the Cricopharyngeal Muscle. This procedure is most often done in the operating room. Cricopharyngeal myotomy, or cutting the Cricopharyngeal Muscle with a laser or surgical instrument, can be done either endoscopically (through the mouth without any incisions on the neck) or through the neck skin, depending on the patient.
Treatment of cricopharyngeal muscle dysfunction can provide significant improvement in swallowing and quality of life. Duration of improvement often depends on the underlying cause of the dysfunction. It is not uncommon for patients with good outcomes after stretching to proceed to Cricopharyngeal Muscle myotomy for a permanent solution if you and your doctor decide this is the best course of action for you. Overall, most patients do well with procedures and experience few side effects or complications.
Copyright 2021. American Academy of Otolaryngology–Head and Neck Surgery Foundation. Last reviewed April 2020.
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